Nutrition in Paediatric Critical Care
- Conditions
- ICUNutritionPaediatric
- Registration Number
- NCT06695078
- Brief Summary
This is a multi-centre prospective cohort study of nutrition in paediatric critical care in Australia and New Zealand. The study is planned to run in parallel with the adult ICU cohort study, NUTRIENT. Two study periods are proposed with the first in late 2024 and the second in 2026. This observational study seeks to determine the following (although not limited to) descriptive outcomes of interest:
1. Nutritional outcomes, including route of nutrition support (oral, enteral and/or parenteral), energy and protein prescription and provision, and anthropometric measures
2. Patient-centred outcomes, including duration of invasive respiratory support and hospitalisation, and mortality
3. Nutrition service delivery in the PICU and ward settings
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 200
- All patients </=18 years of age
- Admitted to the PICU after 00:00 on the day of the study period commencement
- Admitted to the PICU for >72 hours
- Those previously enrolled during the study period (i.e. those re-admitted to PICU)
- Those for end of life care only
- Those admitted for organ donation
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Energy intake as proportion of estimated requirements Up to day 28 of hospitalization Oral, enteral and parenteral energy intake will be collected and reported as a proportion of estimated requirements; estimation of requirements will be standardised using the Schofield equation and dependent upon the reported phase of critical illness
- Secondary Outcome Measures
Name Time Method Protein intake as proportion of estimated requirements Up to day 28 of hospitalization Oral, enteral and parenteral protein intake will be collected and reported as a proportion of estimated requirements; estimated requirements will be standardised and dependent upon reported phase of critical illness
Route of nutrition provision Up to day 28 of hospitalization Data will be collected on route of nutrition provision (oral, enteral or parenteral); enteral route will be categorised according to type of enteral feeding route
Type of nutrition provision (type of diet or oral/enteral feed/formula) Up to day 28 of hospitalization Data will be collected on the type of nutrition provision, in regards to type of diet and the type of formula or feed provided orally or enterally
Anthropometric measures reported as z-scores Up to day 28 of hospitalization Weight and length/height will be collected (and head circumference for children up to 2 years gestational age); these measures will be reported according to WHO growth standard z-score (up to 2 years age) or CDC growth standard z-scores (2 years age and above)
Multidisciplinary nutrition assessment and intervention Up to day 28 of hospitalization Data will be collected on the frequency of nutrition assessment or intervention, including which profession completed the assessment or intervention (i.e. dietetics, medical, nursing or other)
Duration of invasive ventilation Up to day 28 of hospitalization Data will be collected on the duration of invasive ventilation
Duration of PICU and hospital admission Up to day 28 of hospitalization Duration of PICU and overall hospital admission will be collected
Trial Locations
- Locations (11)
Women's and Children's Hospital Adelaide
🇦🇺Adelaide, Australia
Queensland Children's Hospital
🇦🇺Brisbane, Australia
Royal Hobart Hospital
🇦🇺Hobart, Australia
Monash Children's Hospital
🇦🇺Melbourne, Australia
The Royal Children's Hospital Melbourne
🇦🇺Melbourne, Australia
Perth Children's Hospital
🇦🇺Perth, Australia
Sunshine Coast Hospital
🇦🇺Sunshine Coast, Australia
John Hunter Children's Hospital
🇦🇺Sydney, Australia
Sydney Children's Hopsital
🇦🇺Sydney, Australia
The Children's Hospital at Westmead
🇦🇺Sydney, Australia
Starship Children's Hospital
🇳🇿Auckland, New Zealand