Probiotics clinical trials on allergic rhinitis
- Conditions
- Diseases of the respiratory system
- Registration Number
- KCT0002661
- Lead Sponsor
- VP Healthcare
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 80
Those who agreed to attend the protocol with the permission from one of their parent.
Children who aged from 6 to <19 years.
Children who show allergic rhinitis-compatible symptoms for more than 2 consecutive years.
Children who gets more than 2 points of nasal symptoms during the run-in (from VIsit 1 to visit 2) periods.
Children who did not take allergic drugs to relieve the nasal symptoms during the run-in period.
Those who are taking medicine that might affect the allergic rhinitis control.
Those who took the systemic steroid, nasal cromolyn, and loratadine 2 weeks before the screening.
Those who took probiotics-containing food consecutively (more than 4 times/ week).
Those who are under a treatment of gastritis or gastric ulcer.
Those who are under the asthma treatment
Those who suffered a severe neurovascular diseases, cardiac diseases for the recent 6 months (for the stable subjects the investigater can approve the participitation)
Those who sufferes from the psychiatric diseases (depression, schizophrenia, drug addiction, etc)
Those who the PI reasoned inappropriate to take part in the study.
Recent or current attendence to another clinical study
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total Nasal Symptom Score (TNSS)
- Secondary Outcome Measures
Name Time Method Quality of Life questionnaire in Korean Children with Allergic Rhinitis (QoL-KCAR);2 weeks after consumption;Specific IgE (Dp, Df);Eosinophil count;Eotaxin;IgG4(Dp, Df);IL-4, IL-5, IL-10, IL-13, IFN-g