MRI measurements of the brain vessel walls in patients with cerebral vasculitis
Recruiting
- Conditions
- Cerebral vasculitis, MRI, vessel wall
- Registration Number
- NL-OMON24077
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Dieleman, Patterns of intracranial vessel wall changes in relation to ischemic infarcts, Neurology, 2014
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 80
Inclusion Criteria
Inclusion criteria for healthy volunteers
- 18 years or older
Exclusion Criteria
Exclusion criteria for healthy volunteers
- Allergic reaction to gadolinium
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main research question is to compare the diagnostic accuracy of 7T MRI for cerebral vasculitis, with the standard diagnostic practice (SDP). The true nature of the disease will be assessed for all patients at the end of the study by re-evaluation of the patients, assessing either response to treatment or recurrent symptoms (Reference standard, RS). The goal of the study is to compare both the sensitivities and specificities of the two diagnostic tests.
- Secondary Outcome Measures
Name Time Method Our second objective is to compare the intracranial vessel wall abnormalities found in patients to the abnormalities found in healthy volunteers.<br><br /><br /><br>Our third objective is to investigate whether changes of the intracranial vessel wall occur between baseline and follow-up.