Skip to main content
Clinical Trials/NCT04594993
NCT04594993
Active, not recruiting
Not Applicable

INFINITY™ With ADAPTIS™ Technology Total Ankle Replacement Follow-Up

Stryker Trauma and Extremities13 sites in 1 country200 target enrollmentStarted: February 9, 2021Last updated:

Overview

Phase
Not Applicable
Status
Active, not recruiting
Sponsor
Stryker Trauma and Extremities
Enrollment
200
Locations
13
Primary Endpoint
Measure survivorship of INFINITY™ with ADAPTIS™ Technology Total Ankle System at 10 years

Overview

Brief Summary

INFINITY™ with ADAPTIS™ Technology Total Ankle Replacement Follow-up (ITAR2) - Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary/Unilateral and/or bilateral Total Ankle Arthroplasty subjects implanted with INFINITY™ Total Ankle System Number of Subjects 200 patients with up to 13 sites

Detailed Description

The selected design is a multi-center, non-randomized, prospective study of 200 subjects in the US with up to 13 investigational sites and a potential for more as needed to meet the enrollment requirements. The study subjects included are those with ankle joints damaged by severe rheumatoid arthritis, post-traumatic disease, and degenerative arthritis and implanted with the INFINITY™ With ADAPTIS™ Technology Total Ankle System.

Study Design

Study Type
Observational
Observational Model
Other
Time Perspective
Prospective

Eligibility Criteria

Ages
22 Years to — (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Be over 22 years of age at the time of surgery;
  • Diagnosed with unilateral and/or bilateral ankle joint disease;
  • Diagnosed with ankle joint damage from rheumatoid arthritis, post-traumatic, or degenerative arthritis;
  • Willing and able to consent to participate (written, informed consent;
  • Willing and able to attend the requested follow-up visits;
  • A clinical decision has been made to use INFINITY™ with ADAPTIS™ Technology Total Ankle System replacement prior to enrollment.

Exclusion Criteria

  • Subjects with an ankle condition, as determined by the investigator, to be an inappropriate candidate for a total ankle replacement;
  • Subjects requiring revision total ankle replacement of the ankle being considered for study

Outcomes

Primary Outcomes

Measure survivorship of INFINITY™ with ADAPTIS™ Technology Total Ankle System at 10 years

Time Frame: 10 years

Assess the 10-year survivorship of 200 patients implanted with the INFINITY™ with ADAPTIS™ Technology Total Ankle System is non-inferior to other, similar devices.

Secondary Outcomes

  • PROMIS® Global Health Questionnaire(10 years)
  • Ankle Osteoarthritis Score (AOS) Questionnaire(10 years)
  • Patient Satisfaction of Total Ankle Replacement (TAR)(10 years)
  • Radiographic Evaluation- Physician Reported Questionnaire(10 years)
  • Foot & Ankle Observational Score (FAOS) questionnaire.(10 years)

Investigators

Sponsor
Stryker Trauma and Extremities
Sponsor Class
Industry
Responsible Party
Sponsor

Study Sites (13)

Loading locations...

Similar Trials