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Clinical Trials/NCT03277989
NCT03277989
Terminated
Not Applicable

INFINITY™Total Ankle Replacement Follow-up

Stryker Trauma and Extremities9 sites in 1 country155 target enrollmentOctober 9, 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Arthritis, Rheumatoid
Sponsor
Stryker Trauma and Extremities
Enrollment
155
Locations
9
Primary Endpoint
Survivorship at 10 Years
Status
Terminated
Last Updated
last year

Overview

Brief Summary

Study Title INFINITY™Total Ankle Replacement Follow-up (ITAR) Study Design Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary/Unilateral and/or bilateral Total Ankle Arthroplasty subjects implanted with INFINITY™ Total Ankle System Number of Subjects 150 with 9 sites

Detailed Description

The primary outcome measure of this post-market clinical observational study is to collect data relating to the INFINITY™ Total Ankle System survivorship at 10 years. The secondary outcome measures are to characterize the improvements after implantation over a 10 year period using patient reported outcome measures related to quality of life, pain and functional improvements, safety of the implants, as well as radiographic assessments (X-Rays) The outcome measures collected in this study will be analyzed and reported as required for local, regional, and country requirements (i.e., regulatory authorities and notified bodies).

Registry
clinicaltrials.gov
Start Date
October 9, 2017
End Date
March 31, 2023
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Sponsor
Stryker Trauma and Extremities
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Be 21 years of age or older at the time of surgery;
  • Diagnosed with unilateral and/or bilateral ankle joint disease;
  • Diagnosed with ankle joint damage from rheumatoid arthritis, post-traumatic, or degenerative arthritis;
  • Willing and able to consent to participate (written, informed consent;
  • Willing and able to attend the requested follow-up visits;
  • A clinical decision has been made to use INFINITY™ Total Ankle System replacement prior to enrollment in the research.

Exclusion Criteria

  • Subjects with an ankle condition, as determined by the investigator, to be an inappropriate candidate for a total ankle replacement;
  • Subjects requiring revision total ankle replacement of the ankle being considered for study.

Outcomes

Primary Outcomes

Survivorship at 10 Years

Time Frame: 10 years

The primary endpoint is a survivorship rate at 10 years as defined with a Kaplan Meier survivorship analysis.

Secondary Outcomes

  • Radiographic Evaluation-physician Reported Questionnaire(Pre-op through 2 years)
  • Ankle Osteoarthritis Score (AOS)(Pre-op though 2 years)
  • PROMIS Scale v1.2- Global Health(2 years)
  • FAOS Questionnaire(2 years)
  • TAR Satisfaction Questionnaire(Pre-op through 2 years)

Study Sites (9)

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