Organoids of Barrett*s esophagus: <br>a feasibility study and creation of a Biobank <br>

Phase 2

Completed

• Conditions: Barrett's esophagus; 10017969

• Registration Number: NL-OMON44335
• Lead Sponsor: Radboud Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 10

Inclusion Criteria

- Confirmed histological diagnosis of Barrett*s esophagus after previous endoscopy.
- Participant in the Barrett*s esophagus surveillance program.

Exclusion Criteria

a) Age < 18 years
b) Previous thoracic radiotherapy.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoint is successful growth of Barrett*s organoids and to test<br /><br>pharmacological and chemotherapeutical agents in vitro on the cultured<br /><br>organoids.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>To create a small Biobank (of 10 patients) for further study</p><br>