Molecular alterations in Barrett's esophagus by the treatment with proton pump inhibitors or Helicobacter pylori eradicatio
Not Applicable
- Conditions
- Barrett's esophagus
- Registration Number
- JPRN-UMIN000006207
- Lead Sponsor
- Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 38
Inclusion Criteria
Not provided
Exclusion Criteria
(1)Patients with malignancy in other organs (2)Patients with having allergy to PPIs or drugs used for H. pylori eradication (3)Patients who are regularly taking PPIs or non-steroidal anti-inflammatory drugs (4)Past episode of H. pylori treatment (5)Patients with having a past history of esophagectomy or gastrectomy (6)Patients who have determined by the physicians to have any reasons of unqualified
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes of biomarkers related to pathogenesis of Barrett's esophagus are evaluated at baseline and 1-yr after intervention with/without PPI administration in H. pylori negative patients and H. pylori eradication in H. pylori positive patients
- Secondary Outcome Measures
Name Time Method