An evaluation of two eight-month regimens of chemotherapy for the treatment of newly diagnosed pulmonary tuberculosis: A multicentre, single-blinded, randomised controlled trial

International Union Against Tuberculosis and Lung Disease (France)0 个研究点目标入组 1,500 人开始时间: 2010年4月15日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Age 15 to 65 years
•2. Two sputum specimens positive for acid-fast bacilli on direct smear microscopy
•3. No previous anti-tuberculosis chemotherapy for more than one month
•4. A specific home address readily accessible for visiting in case of a failure to attend
•5. Informed consent given and agreed to participate in the study and to give a sample of blood, urine or saliva for HIV testing

•1. So ill they were thought unlikely to survive the initial weeks of treatment
•2. Presence of extra-pulmonary tuberculosis
•3. Concomitant diseases likely to prejudice the response to, or assessment of, treatment such as
•3.1. Diabetes
•3.2. Liver disease
•3.3. Nephritis
•3.4. Blood disorders
•3.5. Epilepsy
•3.6. Peripheral neuritis
•4. Known to be pregnant
•5. Suffering from a psychiatric illness or alcoholism

发起方

International Union Against Tuberculosis and Lung Disease (France)