Effects of a computer-assisted training on social cognition in Borderline Personality Disorder

Not Applicable

Conditions: F60.31

Registration Number: DRKS00014032

Lead Sponsor: ZI Mannheim

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 60

Inclusion Criteria

Borderline-Personality Disorder (BPD): BPD diagnosis with International Personality Disorder Examination (>=5 out of 9 criteria following DSM-5, IPDE, Loranger, 1999)

Exclusion Criteria

Diagnosis of schizophenic disorder or bipolar I disorder, substance dependency during the last year, current substance abuse, epilepsy, brain trauma, brain tumor or other neurological diseases
additional exclusion criteria for participating in the fmrt tasks: BMI<16.5, metall implants, permanent make-up, claustrophobia, left-handedness

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cognitive and social-cognitive processes are assessed prior and following the training with help of a task battery (social-cognitive processes: perception and evaluation of positive social-emotional information including a facial emotion intensity rating tasks (Thome et al., 2016), perception of social cues during a virtual reality setting and its effects on subsequent interaction behavior (Liebke et al. in revision), evaluation and anticipation of social scenes (adapted version of the fMRT task introduced by Herwig et al., 2010); cognitive processes: trail-making test, N-back, word/attribution fluency). During one cognitive and one social cognitive task (Anticipation of social scenes, N-back task) neuronal correlates of the processes will be assessed with functional magnetresonancetomography.

Secondary Outcome Measures

Name	Time	Method
social functioning (Social Functioning Scale, Birchwood et al., 1990)<br>loneliness (UCLA Loneliness Scale-R, Russell et al., 1980)<br>rejection sensitivity (Rejection Sensitivity Questionnaire, Bungert et al., 2015)<br>self-esteem (Self-Esteem Scale, Rosenberg, 1965)<br>Ambulatory assessment of frequency and emotional evaluation of social encounters <br>