The Vitamin D Dose-Response Relationship
- Conditions
- Vitamin D Status
- Interventions
- Radiation: UVB
- Registration Number
- NCT01074541
- Lead Sponsor
- Bispebjerg Hospital
- Brief Summary
The purpose of the study is to determine the importance of the UV intensity and the UVB dose on the Vitamin D response after UVB.
- Detailed Description
The work is addressing vitamin D production after UVB exposure and explore the importance of UVB dose and UV intensity. Four different UVB doses and four different UV intensities are used to explore these relationships.
Many assumptions have been made concerning the vitamin D production after UVB exposure but only few studies exist.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 55
- 18-65 years
- Healthy
- Sun bed use
- Holiday or business travel south of 45 degrees latitude during trial
- Illness
- Drug addiction
- Pregnancy
- Lactating
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Group 1 UVB UV intensity 10 MIN Group 2 UVB UV intensity 5 MIN Group 3 UVB UV intensity 1 MIN Group 4 UVB UV intensity 20 MIN
- Primary Outcome Measures
Name Time Method Vitamin D (nmol/l) 2 days after exposure Vitamin D measured in a blood sample to define the dose-response relationship between UVB dose, UV intensity and Vitamin D production in the skin after UVB exposure.
- Secondary Outcome Measures
Name Time Method Other parameters 2 days after radiation To invesitage whether other parameters like sex, BMI, Diet etc. influences the vitamin D production after UVB exposure.
Trial Locations
- Locations (1)
Bispebjerg Hospital, Department of Dermatology
🇩🇰Copenhagen NV, NV, Denmark