Alternative Treatments of Vitamin D Deficiency

Not Applicable

Completed

• Conditions: Vitamin D Deficiency
• Interventions: Radiation: Narrowband UVB; Dietary Supplement: Vitamin D and calcium

• Registration Number: NCT01512537
• Lead Sponsor: Lund University

Brief Summary

The purpose of the study is to compare the efficiency of UVB and vitamin D supplementation in treatment of vitamin D deficiency.

Detailed Description

Patients with vitamin D deficiency were recruited and randomized into two groups, one exposed to UVB and the other receiving oral treatment with vitamin D supplementation.

Study Timeline

• Study Start: 2010-02
• Primary Completion: 2011-04
• Study Completion: 2011-11
• Study First Submitted: 2011-12-22
• Status Verified: 2012-01
• Study First Submitted QC: 2012-01-15
• Last Update Submitted: 2012-01-15
• Study First Posted: 2012-01-19
• Last Update Posted: 2012-01-19

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

• Vitamin D deficiency (< 25 nmol/l)
• Age 15 or above

Exclusion Criteria

• Travel south of 45 degrees latitude during the trial.
• Ongoing treatment with vitamin D supplementation.
• Intake of light sensitive medicine, such as tetracyclins.
• Skin light eruptions

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
UVB	Narrowband UVB	UVB exposed group
Oral vitamin D tablet	Vitamin D and calcium	Vitamin D supplementation

Primary Outcome Measures

Name	Time	Method
Vitamin D (nmol/l).	Week 0	Vitamin D was measured in a bloodsample to determine baseline status.
Vitamin D (nmol/l)	Week 3	Vitamin D was measured in a bloodsample to follow the change from baseline in vitamin D level at week 3.
Vitamin D	Week 6	Vitamin D was measured in a bloodsample to follow the change from baseline in vitamin D level at week 6.

Secondary Outcome Measures

Name	Time	Method
Parathyroid hormone (pmol/l).	Week 0, 3 and 6.	To investigate whether parathyrodiea hormone changes during the study.
Albumin (g/l).	Week 0, 3 and 6.	To investigate whether albumin changes during the study.
Calcium (mmol/l)	Week 0, 3 and 6.	To investigate whether calcium changes during the study.
Hemoglobin A 1c (percentage HbA1c of total hemoglobin).	Week 0, 3 and 6.	To investigate whether HbA1c changes during the study.

Trial Locations

Locations (1)

Department of Dermatology, Lund University Malmoe; 🇸🇪 Malmoe, Sweden