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临床试验/NCT05354284
NCT05354284进行中(未招募)不适用

Physical and Mental Health Among Sexual and Gender Minorities During

Linkoeping University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2021年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
进行中(未招募)
发起方
入组人数
200
试验地点
1
主要终点
BIrth experience

研究概览

简要总结

Mental illness increases the risk of adverse birth outcomes (e.g. preterm birth), obstetric complications (e.g. emergency caesarean, birth injuries), and birth trauma. Sexual and gender minority (SGM) people on average experience increased mental illness. Therefore these risks are increased, with risk of prolonged ill health. Despite this, research in this area is scanty. The present project will provide important knowledge for improving the reproductive health of SGM people.

The overall purpose of the project is to increase knowledge about physical and mental health (including fear of childbirth) during pregnancy and postpartum in SGM people. The project has the following aims:

PART I 2017 - 2021Pilotstudy

  1. To study fear of childbirth (FOC) among SGM people in Sweden; prevalence and factors associated to FOC
  2. To investigate reasons to and consequences of FOC in SGM people

PART II 2022-2027 Main study 3. To explore whether SGM people in Sweden have an increased incidence of mental illness during and after pregnancy, adverse birth outcomes, obstetric complications and birth trauma. 4. To explore how pre- and postnatal mental health, minority stress, and fear of childbirth correlate to birth outcomes, birth experience, and obstetric complications in SGM people. This is important for identifying specific risk factors for difficult births, and to explore postpartum health effects. 5. To explore in-depth how SGM people have experienced adverse birth outcomes, obstetric complications, and birth trauma, with a specific focus on minority stress and experiences of care during and after pregnancy and childbirth.

详细描述

Mental illness (fear of childbirth included) during pregnancy increases the risk of adverse birth outcomes (e.g. preterm birth, low birth weight), obstetric complications (e.g. emergency caesarean, instrumental birth, major haemorrhage, perineal laceration), postpartum depression, and postpartum PTSD. Further, social vulnerability, such as belonging to an ethnic minority group, has also been shown to increase the risk of these birth-related complications.

It is also well known that sexual and gender minority (SGM) people (e.g. lesbian and bisexual women, transgender and genderqueer people) on average experience increased mental illness. This is thought to be the consequences of exposure to minority stress.

When stressors related to pregnancy and birth are added to the prolonged minority stress, mental illness increases as a consequence. Previous research shows increased depression, anxiety, and feelings of loneliness and dysphoria during pregnancy, as well as increased risk of postpartum depression, in SGM people.

This indicates that SGM people are at increased risk of adverse birth outcomes, obstetric complications, and traumatic birth experiences, followed by an increased risk of long-term negative effects on their mental and reproductive health. There is very little research on these issues. An American study found that incidence of preterm birth, low birth weight, stillbirth, and caesarean are increased among sexual minority women. However, there are no studies on birth outcomes in gender minority people. Nor are there any publications on obstetric complications or birth trauma in gender or sexual minority people. The present project fills these research gaps.

The data of a pilot study in pregnant SGM people shows an increased prevalence in this group. Fear of childbirth increases the risk of obstetric complications, and is a common reason for requested caesarean. There is unpublished clinical data on caesarean in SGM people that shows a huge overrepresentation in this group. Thus, the study preliminary data indicates that SGM people are at risk of adverse birth outcomes, obstetric complications, and birth trauma, and highlights the need for researching these issues thoroughly.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Self defined LBTQ persons

排除标准

  • age under 18, not able to read Swedish

结局指标

主要结局

BIrth experience

时间窗: 3 moths postpartum

Childbirth Experience Questionnaire (1-4 high levels more positive rating)

Obstetrical complications

时间窗: 3 months postpartum

Qualitative interviews

Fear of child birth

时间窗: At inclusion

Wijma Delivery expectancy / experience questionnaire (min 0-max 165. the higher the more severe fear of childbirth)

Mental illness

时间窗: 3 moths postpartum

Qualitative interviews

次要结局

  • Life quality(At inclusion and 1 year after birth)
  • Posttraumatic stress(At inclusion, 3 moths after birth and 1 year after birth)
  • Anxiety(At inclusion, 3 moths after birth and 1 year after birth)
  • Traumatic Birth(3 moths after birth)
  • Depression(At inclusion, 3 months after birth and 1 year after birth)

研究者

发起方
Linkoeping University
申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Anna Malmquist

Associated professor

Linkoeping University

研究点 (1)

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