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Clinical Trials/NCT06737263
NCT06737263
Active, not recruiting
Not Applicable

Comparison of BioHPP (High Performance Polymer) - vs Titanium- vs Zirconia Abutments A Randomized Controlled Clinical Trial

Medical University of Graz1 site in 1 country60 target enrollmentFebruary 13, 2019

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Peri-implant Soft Tissue Healing
Sponsor
Medical University of Graz
Enrollment
60
Locations
1
Primary Endpoint
Mean Bone level
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

The project is a prospective, randomized, controlled study. The material BioHPP (High Performance Polymer) is compared with the gold-standard abutment materials titanium and zirconia in terms of peri-implant soft tissue healing.

Detailed Description

A total of 60 participants are divided into three groups of 20 persons each. One group receives BioHPP abutments, while the two control groups receive titanium or zirconia abutments. The patients are provided with closed healing dental implants. After 3 months, following implant exposure and optical impression, the implants are restored with individual abutments. Follow-up appointments are scheduled at 3, 6, 12, 24, and 36 months after implantation. During these visits, implant healing is assessed based on clinical parameters such as probing depth, plaque index, mean bone level, and bleeding on probing.

Registry
clinicaltrials.gov
Start Date
February 13, 2019
End Date
August 2026
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Medical University of Graz
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Written informed consent
  • The patients must be between 18 and 99 years old.
  • non-smokers, former smokers, or light smokers (fewer than 10 cigarettes per day).
  • ASA ( American Society of Anesthesiologists) Class I or II.
  • There must be no pregnancy or breastfeeding period.
  • the patients must have an edentulous section of up to 3 teeth in the maxillary or mandibular region, where it is possible to place an implant
  • no allergy to any of the study-related materials

Exclusion Criteria

  • Patients under 18 or over 99 years old.
  • Heavy smokers or former heavy smokers who quit less than five years ago
  • Existing pregnancy or breastfeeding period.
  • Individuals classified as ASA Class III to V.
  • Presence of a polymer allergy.
  • Patients with severe systemic diseases, immune deficiencies, or on corticosteroid medication.
  • Patients undergoing local radiation or bisphosphonate therapy.
  • Patients requiring sinus augmentation or soft tissue augmentation.
  • Participation in another dental study

Outcomes

Primary Outcomes

Mean Bone level

Time Frame: 36 months after implantation

in millimeters

Secondary Outcomes

  • Plaque index(36 months after implantation)
  • Bleeding on probing(36 months after implantation)
  • Probing depth(36 months after implantation)
  • Occurrence of complications(36 months after implantation)

Study Sites (1)

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