Rehabilitation trial using curara(R) for patients with cerebrovascular diseases

Phase 2

• Conditions: cerebrovascular disease (with hemiplegia)

• Registration Number: JPRN-jRCTs032180163
• Lead Sponsor: Yoshida Kunihiro

Brief Summary

We failed to find any statistically significant differences in the primary and secondary outcome measures between two groups. It is likely 10 m walking time is the best candidate for the primary outcome measure, but the baseline characteristics or entry criteria should be reconsidered more carefully.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-02-27
• Study Completion: 2020-06-06
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

1) Patients with cerebrovascular disease (CVD) presenting with hemiplegia
2) Age: 20 years <= at entry
3) Duration after onset ranges from 14 to 90 days
4) Able to walk 10 m (even with walking aids such as cane or walker)
5) Able to keep admission in Kakeyu-Misayama Rehabilitation Center, Kakeyu Hospital during the study
6) Berg balance Scale: 26<=
7) Written informed consent for the study

Exclusion Criteria

1) Possible causes for gait disturbance other than CVD
2) Not fulfil the body-size criteria for curara(R) model 4
3) Researchers judge the participants inappropriate for the study (for example, severe dementia or psychiatric symptoms, severe spasticity or joint contracture of paralyzed leg, etc.)

Study & Design

• Study Type: Interventional
• Study Design: Not specified