Impact of physical exercises on inflammatory markers, fatigue, quality of life in prostate cancer me
- Conditions
- Prostate cancerCancer
- Registration Number
- ISRCTN80765858
- Lead Sponsor
- Greater Poland Cancer Centre
- Brief Summary
2017 results in https://pubmed.ncbi.nlm.nih.gov/28075422/ (added 12/05/2021)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Male
- Target Recruitment
- 72
1. Aged between 18 and 75 years
2. Scheduled ADT (LH-analogue 10.8 mg every 3 months) planned to continue for a total period of 36 months (3 to 5 months prior to RT, during and after completion)
3. RT received a total dose of 76 Gy in 38 fractions (in the first phase of therapy, the pelvic lymph nodes along with the prostate gland and seminal vesicles were subjected to a dose of 46 Gy at 2 Gy fractions and in the second phase of therapy the irradiated volume was limited to prostate gland plus seminal vesicles to a total dose of 76 Gy),
4. Good general condition (Eastern Cooperative Oncology Group - ECOG- performance status 0-1)
1. Distant metastases and/or disease progression resulting in RT or the introduction of chemotherapy
2. Insufficiently controlled arterial hypertension or cardiac diseases resulting in circulation failure (above Stage II Heart Failure according to the New York Heart Association)
3. Insufficiently controlled metabolic diseases, endocrinological, rheumatic, and absorption disorders
4. Other tumours
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. Efficacy of physical exercises (data from questionnaires)<br> 2. Blood inflammation markers<br> 3. Assessment of functional capacity, fatigue and QoL during PCa treatment<br><br> They are measured before radiotherapy ( baseline), after 8 weeks, and after 10 months (12 month follow-up).<br>
- Secondary Outcome Measures
Name Time Method Correlation (the relationship) between changes in inflammatory parameters with fatigue and QoL scores.