The Impact of Artificial Sunlight on Human Sleep and Circadian Rhythms

Not Applicable

Completed

• Conditions: Mood; Sleep; Circadian Dysregulation
• Interventions: Device: Light

• Registration Number: NCT03636360
• Lead Sponsor: VA Palo Alto Health Care System

Brief Summary

The purpose of this study is to examine, in healthy controls, whether LED lighting that has a color spectrum similar to that of sunlight is able to differentially impact mood, circadian rhythms, sleep, and behavior, as compared to standard fluorescent lighting.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-08-02
• Study First Submitted QC: 2018-08-15
• Study First Posted: 2018-08-17
• Study Start: 2019-07-01
• Status Verified: 2021-03
• Primary Completion: 2021-03-01
• Study Completion: 2021-03-01
• Last Update Submitted: 2021-03-29
• Last Update Posted: 2021-03-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Good self-reported health
• Normal color vision

Exclusion Criteria

• No sleep disorders
• No extreme chronotype
• Regular smoker
• Significant hearing loss
• Depression
• Alcohol use disorder
• Use of illegal drugs
• Pregnant

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
LED	Light	Standard LED lighting
Dim	Light	Dim fluorescent light with same spectrum as "Fluorescent" condition
LED - Sunlike	Light	LED lighting with spectral pattern similar to that of sunlight
Fluorescent	Light	Fluorescent light at same illuminance (lux) as LED light

Primary Outcome Measures

Name	Time	Method
Alertness	15 hours	Change in median reaction time score on the auditory psychomotor vigilance test
Melatonin suppression	3 hours	Amount of reduction in the concentration of salivary melatonin concentrations during an experimental light stimulus

Secondary Outcome Measures

Name	Time	Method
Mood	15 hours	Change in total positive and negative affect scores on the Positive and Negative Affect Schedule (PANAS)

Trial Locations

Locations (1)

VA Palo Alto Health Care System; 🇺🇸 Palo Alto, California, United States