Benefits and Risks of Artificial Light Exposure: Characterisation of Effects on Alertness, Sleep, Cognitive Performance, Mood and Biological Rhythms
Not Applicable
Recruiting
- Conditions
- Human Sleep and Chronobiology
- Registration Number
- NCT05232383
- Lead Sponsor
- University Hospital, Strasbourg, France
- Brief Summary
The purpose of this project is to study the influence of light on sleep, wakefulness, EEG activity and cognitive performances.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 96
Inclusion Criteria
- Male or female
- Aged 18 to 40 years
- With a hint of Bodymass index (BMI) between 17 and 30 kg.m - 2
- healthy subject determined by a clinical examination, a psychological interview, a blood test, a urine analysis
- Subject with a score<6 questionnaire PSQI ("Sleep Questionnaire Pittsburgh")
- Subject agreeing to maintain a regular sleep/wake rhythm during the study
- Subject agreeing to refrain from caffeine, nicotine, alcohol, psychotropic drugs, cannabis or other drugs, during the study
- Signed informed consent
- Subjectaffiliated to a social protection scheme
Exclusion Criteria
- somatic diseases: cardiovascular, respiratory, gastrointestinal, hematopoietic, Visual
- immune system diseases
- kidneys and urinary tract diseases
- endocrine and metabolic diseases
- neurological diseases
- infectious diseases
- thrombocytopenia or other malfunction of blood platelets
- Subject with risk of thrombosis, including subject with a history of phlebitis, smoker under oral contraceptive...
- Subject with an addiction to caffeine, nicotine, alcohol, psychotropic drugs, cannabis, or any other drug
- Subject treatment contraindicated or inadvisable in combination with heparin
- blood donation in the previous 3 months before the inclusion
- Participation in other clinical trials
- Work by shifts in the year preceding the inclusion
- Trans-meridian travel (> 2 time zones) in the month previous the inclusion
- Impossibility to give enlightened information (subject in an emergency situation, understanding difficulties,...)
- Subject under safeguard of justice
- Subject under tutorship or curatorship
- Pregnancy (women of childbearing age)
- Breastfeeding
- Diet incompatible with the study's snack choices
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Cognitive performances assessed using Paced Visual Serial Addition Task (PVSAT) up to 56 hours Paced Visual Serial Addition Task (PVSAT)
Cognitive performances assessed using Psychomotor Vigilance task (PVT) up to 56 hours Psychomotor Vigilance task (PVT)
Cognitive performances assessed using N-back tasks up to 56 hours N-Back-Task 1, 2, 3
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular pathways are affected by red and green light exposure in circadian rhythm regulation?
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Which biomarkers correlate with cognitive performance improvements after polychromatic light exposure in NCT05232383?
What adverse effects are associated with prolonged green light exposure in sleep-wake cycle modulation?
Are there synergistic effects of combining red light therapy with chronopharmacological agents for mood disorders?
Trial Locations
- Locations (1)
Hôpitaux Universitaires de Strasbourg
🇫🇷Strasbourg, France
Hôpitaux Universitaires de Strasbourg🇫🇷Strasbourg, FrancePatrice BOURGIN, MDContact03 88 11 64 30pbourgin@unistra.fr