Effects of Light Intensity Physical Activities on Pre-frontal Cortical Activation, Cognitive Function, Sleepiness and Back Pain

Not Applicable

Active, not recruiting

• Conditions: Pre-frontal Cortical Oxygenated and Deoxygenated Hemoglobin Levels

• Registration Number: NCT06703424
• Lead Sponsor: Chia Yong Hwa Michael

Brief Summary

The objective of this randomised controlled trial is to examine the acute effects of two novel light intensity exercise (sit-cycling and stand-twisting) on prefrontal cortical blood oxygenation, executive functioning, sleepiness and back pain among inactive university students.

The main questions it aims to answer are:

* What are the changes in oxygenated haemoglobin (O2Hb) and deoxygenated hemoglobin (HHb) levels in the prefrontal cortex from baseline to immediately after and 20 minutes after a 5-min bout of S-C and S-T compared to sitting for the same duration?

* What are the changes in executive functioning, specifically, n-back test and Word Colour Stroop test performance from baseline to immediately after and 20 minutes after a bout of S-C and S-T compared to sitting for the same duration?

* How does participants' self-rated daytime sleepiness and back pain after a bout of S-C and S-T compare to sitting for the same duration?

Participants will:

* Perform sit-cycling or stand-twisting for 5 mins (experimental condition) and sit for 5 mins (control condition)

* Wear the functional near-infrared spectroscopy cap on their head throughout the measurements

* Complete 1-back, 2-back test and Word Colour Stroop before, immediately after and 20 minutes after experimental/ control condition

* Have their blood pressure, heart rate taken by a smartwatch

* Complete a daytime sleepiness questionnaire and a back pain questionnaire

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-11
• Status Verified: 2024-11
• Study First Submitted: 2024-11-21
• Study First Submitted QC: 2024-11-21
• Study First Posted: 2024-11-25
• Last Update Submitted: 2024-11-27
• Last Update Posted: 2024-12-02
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 23

Inclusion Criteria

• NTU-NIE university student, between 21 and 30 years old, do not meet physical activity guidelines (150 mins of weekly MVPA)

Exclusion Criteria

• taking blood-pressure lowering medication
• physically active (150 mins or more of weekly MVPA)
• deemed not physically fit to participate in physical activity based on responses to Get Active Questionnaire

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Primary Outcome Measures

Name	Time	Method
1-back test accuracy (%)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Number of correct trials (correct recall)
1-back test reaction time (ms)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Average reaction time across trials
2-back test accuracy (%)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Number of correct trials (correct recall)
2-back test reaction time (ms)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Average reaction time across trials
Colour Word Stroop test accuracy (congruent) (%)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Number of correct trials recall
Colour Word Stroop test accuracy (incongruent) (%)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Number of correct trials recall
Colour Word Stroop test reaction time (congruent) (ms)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Average reaction time across trials
Colour Word Stroop test reaction time (incongruent) (ms)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	Average reaction time across trials
pre-frontal cortical oxygenated hemoglobin levels (micrometre)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	measured by functional near infrared spectroscopy
pre-frontal cortical deoxygenated hemoglobin levels (micrometre)	Pretest, post-test 1 (immediately after experimental condition) and post-test 2 (after post-test 1)	measured by functional near infrared spectroscopy

Trial Locations

Locations (1)

Block 5 Physical Education and Sport Science; 🇸🇬 Singapore, Singapore