Evaluation of Enteral Erythropoietin in prevention of Necrotizing Entrocolits in Very Low Birth Weight infants
Not Applicable
- Conditions
- ecrotizing Enterocolitis of fetus and neonate.Necrotizing Enterocolitis of fetus and neonate
- Registration Number
- IRCT201310164113N4
- Lead Sponsor
- Pediatric Health Research Center of Tabriz University of Medical Sceinces
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 105
Inclusion Criteria
Patients will eligible if they are inborn preterm infants with gestational age of 28 weeks or less or Birth weight 1250 gram or less and they are Appropriate for Gestational Age. Patients will consider ineligible if they have any congenital anomaly of the gastrointestinal tract (i.e., omphalocele, gastroschisis, tracheoesophageal fistula, intestinal perforation), or have other major congenital anomalies (congenital heart disease, neural tube defect, congenital diaphragmatic hernia, Trisomy, etc.).They Also will exclude if the neonates judge as being too ill to be acceptable study candidates; this criterion will set as receiving mechanical ventilation with an FIO2>0.60
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Frequency of Necrotizing Enterocolitis. Timepoint: After third days of birth until discharge from hospital or death. Method of measurement: Clinical evaluation and radiologic finding.;Mortality rate. Timepoint: After third days of birth until discharge from hospital or death. Method of measurement: Clinical evaluation.;Tolerance data included the occurrence of emesis, gastric residuals, diarrhea, bloody stools, abdominal distention. Timepoint: After third days of birth until discharge from hospital or death. Method of measurement: Clinical evaluaion and measurement of abdominal circumference).
- Secondary Outcome Measures
Name Time Method Frequency of Retinopathy Of Prematurity. Timepoint: After 4 weeks of birth. Method of measurement: Ophtalmologic exam by Retinologist.;Frequency of Chronic Lung Disease. Timepoint: After 28 days of birth. Method of measurement: Clinical evaluation of needs of oxygen or respratory support.;Frequency of Intraventricular Hemorrage ( IVH). Timepoint: After one mounths of age. Method of measurement: Ultrasonography by radiologist.