Evaluating the efficacy of Erythropoietin and Intravenous Iron on transfusion requirements in patients undergoing cardiac surgery
Phase 3
Recruiting
- Conditions
- iron deficiency anemia.
- Registration Number
- IRCT20190121042447N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 154
Inclusion Criteria
patient over 18 years old CABG candidate if hemoglobin concentration less than 12 g/dl in women and less than 13 g/dl in men 1-ferritin < 30 mcg/l 2-ferritin 30-100 mcg /l or TSAT<20% OR CRP>5 mg/l
Exclusion Criteria
Patients with uncontrolled hypertension (BP>180/110) -platelet count more than 450,000/mm3 history of thromboembolism, history of seizure, history of malignant disease liver dysfunction(transaminase>3ULN), confirmed renal impairment (serum creatinine[Cr]2 mg/dl), aplastic anemia hypersensitivity to iron history of erythropoeitin use
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Transfusion requirement. Timepoint: before surgery until seven days after surgery. Method of measurement: transfused volume in mili litre.
- Secondary Outcome Measures
Name Time Method Hemoglobin concentration changes. Timepoint: before surgery until seven days after surgery. Method of measurement: labaratory data in mg/dl.