Clinical and radiographic evaluation of Poly Glycolic Acid / Poly Lactic Acid and hydroxyapatite paste in the treatment of periodontal intrabony defects:A randomized controlled clinical trial
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Change in probing depth
研究概览
简要总结
This study is a randomized controlled split mouth clinical trial comparing the clinical and radiographic evaluation of Poly Glycolic Acid/Poly Lactic Acid and hydroxyapatite paste (fisiograft HA paste) with hydroxyapatite bone graft in the treatment of periodontal intrabony defects that will be conducted in Vydehi institute of dental sciences,Bangalore ,India. The primary outcome measures will be change in probing depth,Change in Relative attachment level and percentage of bone fill at the end of 9 months of surgery The secondary outcomes will be Plaque index, Gingival index and clinical attachment level at the end of 9 months of the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Outcome Assessor Blinded
入排标准
- 年龄范围
- 35.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients within the age group of 35 to 60 years.
- •Patients with stage III and stage IV periodontitis according to 2017 world workshop on periodontal and peri implant diseases and conditions.12 Presence of minimum of 16 natural teeth.
- •Presence of bilateral intrabony defects on Maxillary and mandibular premolar and molar teeth with the presence of two wall or three wall intra bony defect detected on radiograph.
排除标准
- •Medically compromised patients Patients on any medications known to affect the outcomes of periodontal therapy.
- •Pregnant or lactating women Smokers or subjects using any form of tobacco 1 wall- intrabony defect Grade II and grade III mobile tooth.
结局指标
主要结局
Change in probing depth
时间窗: Change in probing depth | Change in Relative attachment level at baseline, 3 months 6 months and 9 months | Percentage of bone fill
Change in Relative attachment level
时间窗: Change in probing depth | Change in Relative attachment level at baseline, 3 months 6 months and 9 months | Percentage of bone fill
Percentage of bone fill
时间窗: Change in probing depth | Change in Relative attachment level at baseline, 3 months 6 months and 9 months | Percentage of bone fill
次要结局
- Plaque index by Silness and Loe 1964(Gingival index by Loe and Silness 1963)
研究者
Dr Nileena Dilip
Rajiv Gandhi university of health sciences