NCT01382576已完成不适用
Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity: A Pathophysiological Link Between Inflammation and Impaired Insulin Sensitivity?
Gulhane School of Medicine1 个研究点 分布在 1 个国家目标入组 78 人开始时间: 2010年1月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 78
- 试验地点
- 1
研究概览
简要总结
In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).
详细描述
ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Absence of significant abnormalities on physical examination except hirsutism
- •no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
- •normal thyroid function and prolactin level
- •absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease
排除标准
- •ovarian tumors
- •congenital adrenal hyperplasia or BMI greater than 30 kg/m2
研究者
Aydogan Aydogdu
MD
Gulhane School of Medicine
研究点 (1)
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