Stopping and Preventing Epileptic Seizures Using a Partial Rebreathing Mask
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 10
- 试验地点
- 3
- 主要终点
- Length of epileptic seizure (subgroup 1)
研究概览
简要总结
By enabling a partial rebreathing of expired gas, a moderate respiratory acidosis is induced, without causing hypoxia in the patient.
Based on the scientific literature on the subject, the study hypothesis is that the fall in body pH will be able to stop and/or prevent epileptic brain activity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18-80 years
排除标准
- 未提供
结局指标
主要结局
Length of epileptic seizure (subgroup 1)
时间窗: Duration of mask treatment during acute seizures: approx. 3 minutes from start of mask treatment until end of seizure
Length of epileptic seizure with treatment mask vs. dummy mask
Frequency of epileptic paroxysms (subgroups 2 and 3)
时间窗: Duration of mask treatment: 45 minutes (group 2) or 10 minutes (group 3) during which patient is monitored with EEG
Frequency of epileptic paroxysms as measured by EEG, treatment mask vs. dummy mask
次要结局
- Oxygen saturation during mask treatment(Duration of mask treatment)