Skip to main content
Clinical Trials/NL-OMON38185
NL-OMON38185
Recruiting
Not Applicable

Reducing high respiratory drive to facilitate supported ventilation in ARDS patients: a pilot study - Supported ventilation in ARDS patients

niversitair Medisch Centrum Sint Radboud0 sites12 target enrollmentTBD

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Not specified
Sponsor
niversitair Medisch Centrum Sint Radboud
Enrollment
12
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
TBD
End Date
TBD
Last Updated
2 years ago
Study Type
Interventional

Investigators

Sponsor
niversitair Medisch Centrum Sint Radboud

Eligibility Criteria

Inclusion Criteria

  • age \> 18 year
  • informed consent
  • ARDS according to the Berlin definition
  • RASS \-4/\-5
  • tidal volume \> 8 ml/kg during supported ventilation
  • esophageal EMG catheter with balloons in situ

Exclusion Criteria

  • recent use of muscle relaxants / neuromuscular blocking agents (\< 3 hours)
  • pre\-existent neuromuscular disease (congenital or acquired) or diseases / disorders know to be associated with myopathy including auto\-immune diseases
  • phrenic nerve lesions
  • elevated intracranial pressure or clinical suspicion of elevated intracranial pressure (i.e. neurotrauma)
  • open chest or abdomen
  • pregnancy
  • systolic blood pressure \< 90 mm Hg / mean arterial pressure (MAP) \< 65 mm Hg

Outcomes

Primary Outcomes

Not specified

Similar Trials