Exercise Capacity, Cardiovascular Risk Factors and Disease-related Variables in Axial Spondyloarthritis

Completed

• Conditions: Exercise Capacity; Axial Spondyloarthritis

• Registration Number: NCT04706650
• Lead Sponsor: Muğla Sıtkı Koçman University

Brief Summary

The investigators aimed to study the associations between exercise capacity and cardiovascular (CV) risk factors in axial spondyloarthritis (axSpA) patients and to determine possible relationships with disease-related variables. Thirty eight patients and 38 controls were recruited in our cross-sectional controlled study. Comprehensive systemic and musculoskeletal examinations were carried out in both of the groups. Cardiovascular risk profile data, ASDAS-CRP, 10-year CV event risk, physical activity levels (IPAQ) were recorded. A maximal treadmill exercise test by Bruce protocol was administered to all participants.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-05-15
• Primary Completion: 2014-10-15
• Study Completion: 2014-10-15
• Status Verified: 2021-01
• Study First Submitted: 2021-01-05
• Study First Submitted QC: 2021-01-10
• Last Update Submitted: 2021-01-10
• Study First Posted: 2021-01-13
• Last Update Posted: 2021-01-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

• clinical diagnosis of axial SpA
• must be able to walk

Exclusion Criteria

• established cardiac disease including structural heart diseases,
• uncontrolled hypertension,
• cardiac rhythm disorder,
• unstable angina pectoris,
• chronical renal and/or hepatic disease,
• malignancy,
• neuromuscular disease
• musculoskeletal deformity
• the history of an inflammatory arthritis for control group

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean difference in exercise capacity of axSpA patients and controls	may- october 2014	maximal METs achieved by a maximal treadmill test by Bruce protocol

Secondary Outcome Measures

Name	Time	Method
Mean difference in heart rate recovery of axSpA patients and controls	may- october 2014	peak heart rate achieved by maximal exercise minus heart rate at 1st minute of recovery phase