Effect of Na/K citrate on contrast media-induced acute kidney injury

Phase 3

• Conditions: Acute renal failure.; Acute renal impairment

• Registration Number: IRCT2015011618389N3
• Lead Sponsor: Qom University of Medical Sciences and Health Services Vice chancellor

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

The inclusion criteria are the existence of at least one risk factor of contrast-induced nephropathy, namely: 1- Moderate systolic heart failure [ (EF) Ejection Fraction between 30-45%]2- Diabetes mellitus 3- Older than 75 year-old 4- Moderate renal insufficiency (serum creatinine level between 1/5-2 mg/dl) 5- Hypotension (systolic blood pressure less than 90 mm Hg 6- Anaemia 7- History of hypertension. Exclusion criteria; 1- pregnancy and lactation 2- History of allergic reaction to contrast media 3- Occurrence of cardiogenic shock and pulmonary edema during study 4-Urgent catheterization 5- Serum creatinine level higher than 2 mg/dl and previous history of dialysis 6- Receiving contrast medium 48 h before and after the intervention 7- Receiving diuretics, N-acetylcystein, sodium bicarbonate, theophylline, dopamine, mannitol, fenoldopam, metformin and NSAID’S during the study 8- Requiring to continue hydration therapy (e.g., sepsis condition) 9-Severe heart failure [left ventricular ejection fraction (LVEF) less than 30%]

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified