The comparison of efficacy between intrathecal morphine combined with either selective COX-II inhibitor or acetaminophen and intrathecal morphine alone for analgesia after cesarean section: a randomized control trial

Phase 4

• Conditions: Opioid consumption, quality of pain control, complication and satisfaction in postoperative period of elective cesarean section; Intrathecal morphine, Acetaminophen, COX-II inhibitor, Non-steroidal anti-inflammatory drugs, NSAIDs, Cesarean section

• Registration Number: TCTR20210813001
• Lead Sponsor: /A

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2021-08-13
• Study Completion: 2021-10-22
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Enrolling by invitation
• Sex: Female
• Target Recruitment: 88

Inclusion Criteria

1. Female participant age 18-40 years old undergoing elective cesarean section
2. ASA II
3. BMI 18-40 kg/m2

Exclusion Criteria

1. Patient deny
2. Unable to communicate with researcher
3. Medication allergy or contraindication to medication which will be administered in this study
4. Contraindication of spinal anesthesia
5. Chronic opioid user

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Opioid consumption 24 hours postoperative Collection from PCA machine

Secondary Outcome Measures

Name	Time	Method
Time to first dose opioid rescue Time to first dose opioid rescue Collection from PCA machine,Pain score (NRS) 1,4,8,12,24 hours postoperative Questionaire,Rate of complication 24 hours postoperative Questionaire,Satisfaction score 24 hours postoperative Questionaire