Comparison between efficacy of Clonidine and Dexmedetomidine with Levobupivacaine while being used in Spinal Anesthesia for lower limb surgery in Medical College Kolkata
Phase 4
- Conditions
- Health Condition 1: O- Medical and SurgicalHealth Condition 2: M218- Other specified acquired deformities of limbs
- Registration Number
- CTRI/2023/09/057773
- Lead Sponsor
- Dr Anjana Ghosh Dastidar Bose
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients scheduled for elective lower limb surgeries under spinal anesthesia during the period of data collection.
Patients with physical status ASA-I and ASA-II.
Patients with Mallampati score 1 and 2.
Exclusion Criteria
Patient refusal.
Patients undergoing emergency surgery.
Any known comorbidities.
Patients with uncontrolled diabetes mellitus, heart disease, morbid obesity, vertebral deformity.
Known allergy to drugs to be used in the study.
Previous bleeding disorder or coagulopathy.
Height <150 cm and >170 cm.
Patients suffering from renal or hepatic derangements.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the onset of sensory & motor block. <br/ ><br> <br/ ><br>To compare the duration of sensory and motor block. <br/ ><br> <br/ ><br>To compare the duration of post operative analgesia. <br/ ><br> <br/ ><br>Time to first rescue analgesia.Timepoint: Baseline, 4 weeks, 8 weeks
- Secondary Outcome Measures
Name Time Method To compare the change in vitals of a patient between before & after injection of the above drugs. <br/ ><br> <br/ ><br>To measure the pulse rate via ECG, SPO2 via pulse oximetry. <br/ ><br> <br/ ><br>To compare the changes in blood pressure, pulse rate, product of mean blood pressure and pulse rate. <br/ ><br> <br/ ><br>To check for any adverse effects or abnormal response to the drugs.Timepoint: Baseline, 4 weeks, 8 weeks