ISRCTN87182483进行中（未招募）未知
Can the use of echocardiographic derived myocardial work predict outcomes in patients with severe aortic stenosis prior to transcatheter aortic valve intervention
ewcastle upon Tyne Hospitals NHS Foundation Trust0 个研究点目标入组 140 人开始时间: 2022年12月12日最近更新:
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 140
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Severe aortic stenosis with a peak velocity (>4.0m/s), mean gradient (>40mmHg) and an aortic valve area <1.0cm on transthoracic echocardiography requiring a transcatheter aortic valve intervention.
- •2. Patients with low-flow aortic stenosis (peak gradient <4.0m/s with AVA <1.0cm2) who require a TAVI will also be invited to participate
排除标准
- •1. Age under 18 years old
- •2. Mild or moderate aortic stenosis (<4.0m/s), mean gradient (<40mmHg), and aortic valve area >1.0cm
- •3. Suboptimal image quality which does not allow for quantitative left ventricular function assessment by Biplane Simpson, myocardial deformation imaging and myocardial work
- •4. Poorly controlled arrhythmias or more than moderate mitral regurgitation
- •5. Unable to tolerate a transthoracic echocardiogram
- •6. Do not provide consent
研究者
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