IRCT20210506051200N1尚未招募3 期
Comparison between effects of intravenous infusion Ibuprofen vs Morphine – Paracetamol on Platelet function in patients under supratentorial brain lesions resection
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •All surgeries for supratentorial lesions
- •No history of coagulation disorders
- •No history of gastrointestinal disease
- •No history of liver disease
- •Discontinue drugs that cause coagulation disorders
- •No history of heart disease
- •No history of renal failure (creatinine clearance <70 mL / min, oliguria or dialysis within 28 days before surgery)
- •No history of diabetes
- •No history of asthma
- •Absence of 2 or more of the following:Alanine aminotransferase> 165 U / L, aspartate transaminase>, 120 U / L Alkaline phosphatase> 345 U / L (three cases too normal)
- •Inability to obtain the consent of the patient or companions
- •No history of disorders due to hypersensitivity to ibuprofen, aspirin, nonsteroidal anti-inflammatory drugs, COX-2 inhibitors
- •- Women in non-pregnancy status
- •No long-term use of anticonvulsant drugs
- •No dependence or tolerance on drugs
- •Weight higher than 30 kg
- •No gastrointestinal bleeding during the last 6 weeks
- •Do not take warfarin, lithium or concomitant use of lasix and angiotensin converting enzyme inhibitors
排除标准
- •Hematocrit less than 25% during surgery
- •Reduction of body temperature to less than 36 ° C
研究者
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