IRCT20210506051200N1
Not yet recruiting
Phase 3
Comparison between effects of intravenous infusion Ibuprofen vs Morphine – Paracetamol on Platelet function in patients under supratentorial brain lesions resection
Overview
- Phase
- Phase 3
- Intervention
- Not specified
- Conditions
- Not specified
- Sponsor
- Shahid Beheshti University of Medical Sciences
- Enrollment
- 30
- Status
- Not yet recruiting
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All surgeries for supratentorial lesions
- •No history of coagulation disorders
- •No history of gastrointestinal disease
- •No history of liver disease
- •Discontinue drugs that cause coagulation disorders
- •No history of heart disease
- •No history of renal failure (creatinine clearance \<70 mL / min, oliguria or dialysis within 28 days before surgery)
- •No history of diabetes
- •No history of asthma
- •Absence of 2 or more of the following:Alanine aminotransferase\> 165 U / L, aspartate transaminase\>, 120 U / L Alkaline phosphatase\> 345 U / L (three cases too normal)
Exclusion Criteria
- •Hematocrit less than 25% during surgery
- •Reduction of body temperature to less than 36 ° C
Outcomes
Primary Outcomes
Not specified
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