Epidemiological Description of the Kaposi's Disease in France's Southeast

• Conditions: Kaposi's Disease

• Registration Number: NCT03662828
• Lead Sponsor: Direction Centrale du Service de Santé des Armées

Brief Summary

The purpose of this study is to evaluate the prevalence of the Kaposi's disease in France's southeast on 10 years (from 2007 to 2017)

Detailed Description

Kaposi's disease is a multifocal disease with cutaneous expression in more than 95% of cases.

There are 4 forms : Mediterranean, Endemic (Sub-Saharan Africa), iatrogenic and epidemic (HIV) The physiological hypotheses to explain the disease are not clear. A proliferation of immunity cells in blood vessels and also an undetermined role of the human herpes virus 8 (HHV-8) could be involved.

The treatment is complex and not standardized. There are a lot of different treatments.

The purpose of this study is to evaluate the prevalence and described the characteristics and the treatment of the Kaposi's disease in the France's southeast on 10 years, from 2007 to 2017.

Study Timeline

• Study First Submitted: 2018-07-23
• Study Start: 2018-08-01
• Study First Submitted QC: 2018-09-05
• Study First Posted: 2018-09-10
• Status Verified: 2019-02
• Last Update Submitted: 2019-05-13
• Last Update Posted: 2019-05-14
• Primary Completion: 2020-08
• Study Completion: 2020-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Diagnosed patients with a Kaposi's disease by biopsy from January 2007 to December 2017

Exclusion Criteria

• Opposition to the use of personal data

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of Kaposi's disease	10 years (2007-2017)	Diagnosed patients with biopsy, in France's southeast

Secondary Outcome Measures

Name	Time	Method
Survival analysis	10 years (2007-2017)	mortality rate
Descriptive analysis of the population : sociodemographic	10 years (2007-2017)	sociodemographic characteristics
Descriptive analysis of the population : therapeutic	10 years (2007-2017)	therapeutic care
Descriptive analysis of the population : clinical	10 years (2007-2017)	clinical characteristics
Descriptive analysis of the different form of the Kaposi's disease in the population	10 years (2007-2017)	Mediterranean form, endemic form, iatrogenic form and epidemic form
Descriptive analysis of the population : paraclinical	10 years (2007-2017)	paraclinical characteristics

Trial Locations

Locations (5)

Hôpital d'Instruction des Armées Sainte-Anne; 🇫🇷 Toulon, Var, France

CHU Nice; 🇫🇷 Nice, Alpes-Maritimes, France

HIA Laveran; 🇫🇷 Marseille, Bouche Du Rhone, France

CHI de Fréjus; 🇫🇷 Fréjus, Var, France

Centre Antoine Lacassagne; 🇫🇷 Nice, Alpes-Maritimes, France