Vertex Pharmaceuticals Incorporated
πΊπΈUnited States
- Country
- πΊπΈUnited States
- Ownership
- Public
- Established
- 1989-01-01
- Employees
- 5.4K
- Market Cap
- $123.9B
- Website
- http://www.vrtx.com
Clinical Trials
640
Active:398
Completed:181
Trial Phases
5 Phases
Phase 1:397
Phase 2:65
Phase 3:85
+2 more phases
Drug Approvals
4
FDA:4
Clinical Trials
Distribution across different clinical trial phases (559 trials with phase data)β’ Click on a phase to view related trials
Phase 1
397 (71.0%)Phase 3
85 (15.2%)Phase 2
65 (11.6%)Phase 4
5 (0.9%)Not Applicable
3 (0.5%)phase_1_2
3 (0.5%)phase_2_3
1 (0.2%)Phase 2a Study of VX-407 in Participants With ADPKD Who Have a Subset of PKD1 Gene Variants
Not Applicable
Recruiting
- Conditions
- Autosomal Dominant Polycystic Kidney Disease (ADPKD)
- Interventions
- First Posted Date
- 2025-09-08
- Last Posted Date
- 2025-09-30
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 24
- Registration Number
- NCT07161037
- Locations
- πΊπΈ
Alabama Kidney Research, Alabaster, Alabama, United States
πΊπΈNephrology & Hypertension Associates, PC, Middlebury, Connecticut, United States
πΊπΈRenal Associates, Columbus, Georgia, United States
Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants
Not Applicable
Recruiting
- Conditions
- Autosomal Dominant Polycystic Kidney Disease (ADPKD)
- Interventions
- First Posted Date
- 2025-07-20
- Last Posted Date
- 2025-08-12
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 148
- Registration Number
- NCT07074327
- Locations
- πΊπΈ
Altasciences - Kansas City, Overland Park, Kansas, United States
A Phase 1 Study Evaluating Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants
Phase 1
Recruiting
- Conditions
- Autosomal Dominant Polycystic Kidney Disease (ADPKD)
- Interventions
- Drug: Placebo
- First Posted Date
- 2025-06-15
- Last Posted Date
- 2025-07-15
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 24
- Registration Number
- NCT07022119
- Locations
- πΊπΈ
ICON Lenexa, Lenexa, Kansas, United States
A Study to Evaluate the Relative Bioavailability of Povetacicept Formulations and Bioequivalence of Povetacicept Presentations
- First Posted Date
- 2025-06-08
- Last Posted Date
- 2025-09-18
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 136
- Registration Number
- NCT07010406
- Locations
- πΊπΈ
Celerion - Tempe, Tempe, Arizona, United States
πΊπΈCelerion - Lincoln, Lincoln, Nebraska, United States
A Study of Long-term Safety and Efficacy of VX-670 in Participants With Myotonic Dystrophy Type I
- First Posted Date
- 2025-04-14
- Last Posted Date
- 2025-08-27
- Lead Sponsor
- Vertex Pharmaceuticals Incorporated
- Target Recruit Count
- 36
- Registration Number
- NCT06926621
- Locations
- π¨π¦
Montreal Neurological Institute-Hospital, Montreal, Canada
π¦πΊWesley Research Institute, Auchenflower, Australia
π¦πΊNeuroscience Clinical Trials Unit, Alfred Brain, Melbourne, Australia
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