Role of individualized homoeopathic medicines in the treatment of nasal inferior turbinate hypertrophy in adolescents and adults: An open-label, single-arm, quasi-experimental study

Nasal turbinate hypertrophy is Hypertrophy (enlargement) of nasal turbinates. Inferior turbinate hypertrophy, a condition where the tissue on the lateral (outside) walls of the nose are too large, causing nasal obstruction. While the worldwide prevalence of inferior turbinate hypertrophy is unknown, a large study by Clark et al, of over 1900 patients with sinonasal complaints revealed that 72% suffered from hypertrophied turbinates. However, this narrowing of the nasal cavity affects the physiological functions of the nasal mucosa, causing problems such as mouth breathing, dry oropharynx, nasal talking, sleep disorders, snoring, nasal congestion, stuffy nose when lying down, and secretions Nasal congestion may affect general health also causes irritability, fatigue, decreased quality of life. The treatment of inferior turbinate hypertrophy has been actively debated for over a century. The main goal of treatment is to minimize the symptoms and extent of hypertrophy of ITH. Although not life-threatening, chronic nasal obstruction significantly impairs patient’s quality of life affecting their daily social and working activities. Though the use of homoeopathic medicines is extensive globally to treat the condition, Research on nasal ITH in homoeopathic treatment limited. There is a notable research gap in understanding the effect and mechanism of homoeopathic intervention for nasal ITH. This provides the basis for to conduct an open-label, single-arm trial on 50 participants suffering from nasal ITH  in adolescents and adults using individualized homoeopathic medicines (IHMs) in outpatient departments(OPD) especially ENT and PG2 of D.N.De Homoeopathic Medical College and Hospital , Govt. of WB; 12, Gobindo Khatick Road, Tangra, Kolkata, WB 700046. Primary outcome will be measured by  using Nasal Obstruction Symptom Evaluation (NOSE) score; Sino Nasal Outcome Test-22(SNOT-22),  Measure Yourself Medical Outcome Profile version2 (MYMOP-2) questionnaire will be the secondary outcome. All the outcomes will be measured every month up to 3 months. Pre-post changes will be measured using appropriate statistical tests. Results will be published in scientific journals.