ACTRN12615000770561进行中（未招募）未知
A study to evaluate the temporal dynamics of RAS Mutation Emergence in Cell Free DNA (cfDNA) in response to first-line cetuximab anti-EGFR therapy in Patients with Metastatic Colorectal Cancer
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 入组人数
- 36
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 o limit（—）
- 性别
- All
入选标准
- •1. Subjects with histologically confirmed metastatic colorectal cancer
- •2. Systemic treatment will comprise (first line anti-EGFR antibody (cetuximab) therapy in combination with either irinotecan-based (FOLFIRI) or oxaliplatin-based (FOLFOX) chemotherapy
- •3. A representative tumour sample is available for molecular testing
- •4. Has measurable metastatic lesion(s), as defined by RECIST version 1.1.
- •5. ECOG performance status 0-2
排除标准
- •1. History of another primary cancer within the last 3 years, with the exception of non-melanomatous skin cancer and carcinoma in situ of the cervix
- •2. Prior treatment with an anti-EGFR antibody
研究者
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