Role of Cardiac Computed Tomography in Optimising Response to Cardiac Resynchronisation Therapy
Not Applicable
- Conditions
- Heart Failure
- Interventions
- Other: Heart scan
- Registration Number
- NCT02434159
- Lead Sponsor
- University College, London
- Brief Summary
The purpose of this study is to determine if detailed scanning of the heart before biventricular device insertion will improve outcomes for heart failure patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Age > 18, <90
- Patients with moderate or severe heart failure ( NYHA functional class II-IV) due to ischaemic or non-ischaemic cardiomyopathy.
- QRS duration >120ms on 12 lead ECG
- LVEF < 35%
- LVEDD >55 mm
- Patients on optimum medical treatment for heart failure. The doses of these medications have been stable for 3 months.
Exclusion Criteria
- Patients with a cardiac or cerebral ischemic event within the previous three months prior to recruitment
- Patients who had had an atrial arrhythmia within one month prior to recruitment
- Patients with a systolic blood pressure of more than 170 or less than 80 mm Hg
- Patients with a heart rate of more than 140 beats per minute
- Patients with severe renal failure (eGFR < 30)
- Patients with a history of allergy to iodine based contrast agents
- Predicted life expectancy < 1 year
- Pregnancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Scan Heart scan Heart scan prior to device insertion
- Primary Outcome Measures
Name Time Method 6 minute walk test 6 months
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University College London Hospital
🇬🇧London, United Kingdom