MIld to MOderate Acute Pancreatitis: Early naSogastric Tube Feeding Compared With pAncreas Rest (MIMOSA)
Phase 2
Completed
- Conditions
- Acute Pancreatitis
- Interventions
- Procedure: Enteral tube feeding
- Registration Number
- NCT01128478
- Lead Sponsor
- University of Auckland, New Zealand
- Brief Summary
Pain relapse during oral refeeding occurs in at least one-fifth of patients with acute pancreatitis. The study hypothesis is that early administered enteral tube feeding might reduce a risk of pain relapse and shorten the length of hospital stay in patients with acute pancreatitis.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
- diagnosis of acute pancreatitis
- age 18 years or older
- written informed consent
Exclusion Criteria
- > 96 hours after onset of symptoms
- > 24 hours after hospital admission
- organ failure by the time of randomization
- infectious complications before randomization
- received artificial nutrition before randomization
- previously enrolled into the trial
- chronic pancreatitis
- post-ERCP pancreatitis
- intraoperative diagnosis of acute pancreatitis
- pregnancy
- malignancy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Enteral tube feeding Enteral tube feeding Nasogastric tube feeding started within 24 h of hospital admission
- Primary Outcome Measures
Name Time Method Length of hospital stay Up to 3 months
- Secondary Outcome Measures
Name Time Method Hospital readmission Up to 6 months Quality of life Up to 6 months Mortality Up to 6 months Pain relapse Up to 3 months Local and systemic complications Up to 3 months Feeding intolerance Up to 3 months Time to solid oral food tolerated Approx. one week Pain-free time Up to 3 months
Trial Locations
- Locations (1)
University of Auckland
🇳🇿Auckland, New Zealand