Positive and Negative Affects Among Osteoarthritis Patient
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 150
- 试验地点
- 1
- 主要终点
- VIA-72
研究概览
简要总结
Osteoarthritis (OA) is a common and debilitating disease, For the majority of patients, pain in OA is episodic in nature.
The experience of pain is generated or modified by nociception, neuropathic symptoms, psychological and personality factors, genetic influences, past painful experiences, comorbid conditions, and expectations related to future pain Previous studies have shown psychological well-being has been significantly associated with disability in patients with OA, and anxiety has been found to be associated with knee pain in women.
Previous studies also found that there are large interindividual differences among persons with knee osteoarthritis (OA) with respect to psychological function.
Psychological strengths and weaknesses are evaluated among new patient with osteoarthritis presented to joint replacement clinic, to facilitate our understanding of those patients need, and correlating with their radiological and clinical findings. Psychological strengths and weaknesses, positive and negative affects are evaluated in form of questionaires.
Reference:
Adaptation to disability: Applying selective optimization with compensation to the behaviors of older adults with osteoarthritis.
MAM Gignac, C Cott, EM Badley - Psychology and aging, 2002
Analgesic effects of multisensory illusions in osteoarthritis C Preston, R Newport - Rheumatology, 2011
Psychological factors and their relation to osteoarthritis pain BL Wise, J Niu, Y Zhang, N Wang, JM Jordan... - Osteoarthritis Cartilage. , 2010 - Elsevier
详细描述
Introduction:
Osteoarthritis (OA) is a prevalent painful condition that may cause disability among older adults (Cruz-Almeida et al., 2013). Psychological traits and emotional states of patients were found to be correlated with symptoms of OA and daily functioning of patients (Cruz-Almeida et al., 2013; Dezutter et al., 2015).
The experience of pain is generated or modified by nociception, neuropathic symptoms, psychological and personality factors, genetic influences, past painful experiences, comorbid conditions, and expectations related to future pain. Previous studies have shown psychological well-being has been significantly associated with disability in patients with OA, and anxiety has been found to be associated with knee pain in women.
Previous studies also found that there are large interindividual differences among persons with knee osteoarthritis (OA) with respect to psychological function.
Aim of project:
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all new patient present to AHNH clinic referred for osteoarthritis for considering joint replacement
- •Present with knee pain (unilateral or bilateral) contributed by osteoarthritis
排除标准
- •mentally unsound
- •dialectic speaker that difficult to communicate
结局指标
主要结局
VIA-72
时间窗: 1 day
Questions reflect statements that the subject would find desirable.
Kellgren & Lawrence (K & L) grading system
时间窗: 1 day
To classify the severity of knee osteoarthritis (OA)
Oxford knee scores
时间窗: 1 day
Consists of 12 questions that cover function and pain of the knee.
Positive and Negative Affect Scale (PANAS)
时间窗: 1 day
This scale consists of a number of questions that describe different feelings and emotions.
The Centre for Epidemiologic Studies (CES-D Scale)
时间窗: 1 day
A list of the ways the subject might have felt or behaved.
The Chronic Pain Acceptance Questionnaire (CPAQ)
时间窗: 1 day
Statements on feelings on pain as it applies to the subject.
Chronic Pain Coping Inventory (CPCI-42)
时间窗: 1 day
次要结局
未报告次要终点
研究者
Lawrence CM Lau
Principal Investigator
Chinese University of Hong Kong