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A clinical study to evaluate anti-hypertensive and other health benefits of Moringa oleifera leaf extract in patients with essential hypertensio

Phase 2
Conditions
Health Condition 1: I10- Essential (primary) hypertension
Registration Number
CTRI/2024/01/062052
Lead Sponsor
JIPMER Puducherry
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Patients with essential hypertension aged = 18 years, irrespective of gender, with or without other comorbidities, who fulfill the following criteria:

Patients on treatment with stable dose of antihypertensive agents for atleast 1 month and has not yet attained target blood pressure goals (130 mm Hg of systolic and 80 mm Hg of diastolic blood pressure) and not requiring dose escalation or addition of new anti-hypertensive agent according to clinical judgment of the treating physician.

Exclusion Criteria

Patients with secondary hypertension.

Patients with resistant hypertension.

Patients with hypertensive urgency or emergency.

Patients not on stable dose of oral hypoglycemic drugs or insulin for past 1 month.

Pregnant and lactating women, women in reproductive age group not practicing contraceptive measures.

Patients with hepatic impairment (elevated liver enzymes more than 2 times upper normal limit)

Patients with renal impairment (serum Creatinine more than 1.2 mg per dl)

Patients with recent history of coronary artery disease

Patients with peripheral vascular disease.

Patients who had participated in other trials in the past three months.

Patients on other herbal medications.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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