Free Fatty Acids: Threshold Repeatability Study
- Conditions
- Taste, Non-esterified Fatty Acids
- Registration Number
- NCT01550120
- Lead Sponsor
- Purdue University
- Brief Summary
This study seeks to determine if non-esterified fatty acid (NEFA) taste detection thresholds change with repeated testing. Threshold testing for NEFA taste has been reported by a number of laboratories, including our own; however, these studies have reported data for only one testing occasion. The investigators seek to conduct repeated testing to measure the test-retest reliability of these methods. The investigators believe that with repeated exposure to NEFA, a person's sensitivity increases. The investigators are also testing the efficiency of testing by two methods (forced-choice ascending trial versus staircase). Additionally, the association between taste responses, diet and BMI will be explored.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 48
- 18-55 years old
- in good health
- available for three months
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method BMI Baseline Non-esterified fatty acid detection thresholds in humans 6 months
- Secondary Outcome Measures
Name Time Method hunger each visit Visual analog scale
Habitual fat intake Baseline Block Rapid Dietary Fat Screener will be used as well as the ASA-24.
testing method 6 months Comparison of time to maximum sensitivity by participants based on forced-choice versus staircase stimulus presentation techniques.
Trial Locations
- Locations (1)
Purdue University
🇺🇸West Lafayette, Indiana, United States