MedPath

IV Haloperidol for the Treatment of Headache in the ED

Phase 4
Completed
Conditions
Migraine Disorders
Headache
Interventions
Drug: Placebo
Registration Number
NCT02747511
Lead Sponsor
Western Michigan University School of Medicine
Brief Summary

Single center, double-blind, randomized, placebo-controlled trial evaluating analog pain scores in patients who present to the emergency department (ED) with a complaint of headache. A total of 150 patients age 13-55 presenting to the emergency department with headache will be enrolled from October 2015 - October 2016. Patients will be randomized and pain scores and side effects will be recorded at 0, 30, 60, and 90 minutes. Follow-up will be performed by telephone at 24 hours.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
118
Inclusion Criteria
  • Emergency Department patients that complain of headache or migraine
  • Males and females age 13-55
  • English is primary language
Exclusion Criteria
  • Abnormal blood pressure (>200/100)
  • Sudden rapid onsent (normal to worst pain in minutes)
  • Fever
  • Trauma
  • Any history of masses, strokes, head injury or other causes of abnormal anatomy
  • QT greater than 450 ms on EKG
  • Allergy to Haldon
  • Any altered mental status (GCS <15)
  • Pregnancy
  • Any abnormalities on neurologic exam
  • Any clinician concern that would require CT scan of brain
  • Any prisoner or ward of state

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
PlaceboPlacebo-
HaloperidolHaloperidol-
Primary Outcome Measures
NameTimeMethod
>50% reduction in pain per Visual Analog Scale (VAS)90 minute interval
Secondary Outcome Measures
NameTimeMethod
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