Efficacy of Yoga in patients with Metabolic dysfunction associated Steatotic Liver Disease - An open label, Non- Inferiority, Randomised Controlled Trial - Nil

Postgraduate Institute of Medical Education and Research0 个研究点目标入组 0 人开始时间: 待定最近更新: 2024年1月22日

试验速览

暂无简介。

•1)Patients with MASLD: defined by the presence of hepatic steatosis on ultrasound or using CAP parameters (of Fibroscan) together with the presence of at least one of five cardiometabolic criteria after ruling other causes of hepatic steatosis.
•2)Overweight and obese patients as per Asia-Pacific criteria (BMI = 23 and = 25Kg/m2) respectively.
•3)All patients must be on stable doses of medical therapy for hypertension or diabetes for atleast 6 weeks before the study start date.
•4)Be willing and able to participate in the full program.
•5)Be willing and able to functionally participate in all activities set as part of the intervention.
•6)Be able to complete all day-to-day activities and instrumental activities of daily living independently, completely without assistance from others.
•7)Consent to participate in study.

•1)Patients who are not willing to give consent for the study.
•2)Patients who will not be able to carry out yoga and exercise protocol safely, recent fall or > 3 falls in a year, recent hospitalization in 1 month, and those who fail to give consent will be excluded.
•3)The patients with severe cardio-pulmonary disease, coronary artery disease, cardiomyopathy, severe musculoskeletal disease, neuropsychiatric disease, history of cardiovascular accident, active malignancy, hepatocellular carcinoma and, the end-stage renal disease.
•4)Patients with decompensated cirrhosis or post liver transplant patients
•5)Pregnant, lactating women
•6)Patients having prior study enrolment or enrolment in another conflicting study within past 3 months.
•7)Patients taking weight loss drugs or oral antidiabetic medications (GLP-1 analogues and glitazones) or any pharmacotherapy for NASH (Vitamin E and Saroglitazar).
•8)Any patient not meeting any part of the inclusion criteria

发起方