跳至主要内容
临床试验/CTRI/2025/02/081213
CTRI/2025/02/081213尚未招募3 期

Efficacy of Common Yoga Protocol as add on intervention along with Navaka Guggulu in the management of Medoroga w.s.r. to Dyslipidemia an open labelled randomized comparative clinical trial

Institute of Teaching and Research in Ayurveda1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2025年6月1日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
30
试验地点
1
主要终点
1 Relief in symptom of Medoroga

研究概览

简要总结

The fast-growing technology, busy schedules, sedentary lifestyle and changes in dietary habits has made an individual prone to various Life Style Disorders. Dyslipidemia being one of them. Dyslipidemia involves abnormality in levels of any or all lipoproteins in the blood. Dyslipidemia is one of the risk factors for cardiovascular diseases. Worldwide, cardiovascular disease is now one of the most common causes of death. Dyslipidemia can be corelated to Medoroga as described in Ayurveda. High fatty diet (Snighdha, Guru, Pichhila) and Sedentary Lifestyle (Avyayama, Diwaswapa) may contribute to Medoroga. Apart from this nidana, mansika hetu also plays crucial role in manifestation of the disease. Navaka Guggulu has hypolipidemic activity as its maximum ingredients have Rasa – Katu, Virya – Laghu, Ruksha and Ushna, Vipaka – Katu, Vata – Kapha Shamaka. On the otherhand, Yoga is a practice of set of procedures which relieves mind-body stress that increases mental and physical health, which has a role in the improvement of metabolism. Common Yoga Protocol (C.Y.P.) is a standardized protocol for Yoga released by Ministry of AYUSH, Government Of India for International Day of Yoga since 2015, which incorporates practices like Pranadharna, subtle exercises, Asanas, Pranayama and Dhyana. Rationale For Selection of Topic: Dyslipidemia is one such disorder which is identified as a potential risk factor for multiple diseases like cardiovascular diseases, NAFLD, metabolic syndrome and even hypertension. Raised total cholesterol is a major cause of disease burden in the both developed and developing world as a risk factor for ischemic heart disease and stroke. In Gujrat, prevalence of Dyslipidemia according to the ICMR- INDIAB Study 2023 high total cholesterol (>200 mg/dl) is 18.1%, high LDL cholesterol (>130mg/dl) is 16% and high triglycerides (>150mg/dl) is 26.9%. Aim and Objectives: To evaluate the add on effect of Common Yoga Protocol (C.Y.P.) along with Navaka Guggulu in the management of Medoroga. Materials and Methods:30 individuals will be enrolled in two groups. Individuals in Group A will be given Navaka Guggulu for 90 days (2 gm / day divided into 2 doses orally 30 minutes after meals) while volunteers in Group B will be made to practice 60 minutes of Common Yoga Protocol (C.Y.P.) along with Navaka Guggulu (2 gm / day divided into 2 doses orally 30 minutes after meals) for 90 days. Results and Discussion: Data generated during the above study will be present in a Systemic manner as shall be analyzed statically. Where the important points of the review of literature, Conceptual study, Analytical study will be discussed. Follow up: After completion of procedure, 2 follow ups after completion of the treatment at the interval of 15 days.

研究设计

研究类型
Interventional
分配方式
Randomized
盲法
None

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • Willing patients between 18 to 60 years of age and BMI Between 18.5kg/m2 to 29.9 kg/m2 having any 02 symptoms viz.
  • Kshudrashwas, Trisha, Swapna, Krathan, Sadan, Kshut, Sweda, Daurgandhya, Alpa Prana, Alpa Maithuna Anyone or more deranged parameters in the lipid profile Sr. cholesterol (more than 200mg/dl and less than 300mg/dl) Sr. Triglyceride (more than 150mg/dl and less than 350mg/dl) Sr. LDL (more than 130mg/dl) Sr. HDL (less than 40 mg/dl) Sr.VLDL (more than 40mg/dl).

排除标准

  • 1 patients below 18 years and above 60 years of age and who are not willing to participate, not physically fit to perform the common yoga protocol 2 Drug induced dyslipidemia 3 Disease induced secondary dyslipidemia 4 Dyslipidemia chronocity for more than 5 years 7 Females with Metrorrhagia 8 Pregnant or lactating females 9 Patient with other systemic disorders.

结局指标

主要结局

1 Relief in symptom of Medoroga

时间窗: 3 times in 12 weeks

2 Reduction in parameters of lipid profile

时间窗: 3 times in 12 weeks

次要结局

  • 1 Improvement in disturbed Manasbhavas of the patients of Medoroga(2 Reduction in Apo B Lipoprotein)

研究者

发起方
Institute of Teaching and Research in Ayurveda
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Sakshi Jatte

Institute of Teaching and Research in Ayurveda Jamnagar

研究点 (1)

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