EUCTR2007-002940-86-BE
Active, not recruiting
Not Applicable
Sepsis, Endothelial function, and Lipids in critically ill patients with Liver Failure (SELLIFA). Nutritional sub-study : Randomized controlled trial comparing the tolerance on lipid metabolism and safety of isocaloric parenteral nutrition with enteral nutrition. - SELLIFA nutritional trial
Cliniques Universitaires Saint-Luc – Université catholique de Louvain0 sitesJuly 26, 2007
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- iver failure, Liver cirrhosis, critical illness, total nutritional support
- Sponsor
- Cliniques Universitaires Saint-Luc – Université catholique de Louvain
- Status
- Active, not recruiting
- Last Updated
- 11 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- All consecutive patients with a diagnosis of chronic liver failure ;
- •\- Adult patient aged 18 years or above, and less than 85 ;
- •\- Admission to the ICU for an expected period of \> 24 hours;
- •\- Planned total nutritional support;
- •\- Informed consent of the patient or nearest relative.
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1\.2 Adults (18\-64 years) yes
- •F.1\.2\.1 Number of subjects for this age range
- •F.1\.3 Elderly (\>\=65 years) yes
Exclusion Criteria
- •\- Absolute contra\-indications to enteral nutrition : total mechanical ileus, persistent vomiting, high output fistulas, uncertain gastrointestinal anastomosis ;
- •\- Absolute contra\-indications to parenteral nutrition : severe hypertriglyceridemia more than 6 mmol/l (545 mg/dL), severe diabetic ketoacidosis ;
- •\- Age less than 18 years and more than 85 ;
- •\- Pregnancy, including HELLP syndrome ;
- •\- Active malignancy with metastases (localised hepatocellular carcinoma is not an exclusion criteria);
- •\- Systemic chemotherapy in the last 4 weeks (trans\-arterial chemo\-embolisation for localised hepatocellular carcinoma is not an exclusion criteria) ;
- •\- Acquired immunodeficiency syndrome and antiretroviral therapy
Outcomes
Primary Outcomes
Not specified
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