Metabolomic Alterations in the Vascular Compartment in Patients With Sepsis

Terminated

• Conditions: Endothelial Dysfunction

• Registration Number: NCT03655899
• Lead Sponsor: Pär Johansson

Brief Summary

This study will investigate the metabolic alterations of vascular cells caused by sepsis and septic shock

Detailed Description

This study will investigate the metabolic alterations of vascular cells caused by sepsis and septic shock in 60 patients

Study Timeline

• Study First Submitted: 2017-09-26
• Study Start: 2017-10-23
• Study First Submitted QC: 2018-08-29
• Study First Posted: 2018-08-31
• Primary Completion: 2019-03-12
• Study Completion: 2019-03-12
• Status Verified: 2019-09
• Last Update Submitted: 2019-09-10
• Last Update Posted: 2019-09-12

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 37

Inclusion Criteria

• 18 year or older
• Sepsis or Septic shock

Exclusion Criteria

• Pregnant or breastfeeding
• Hemoglobin ≤ 5.0 mmol/L
• Platelets ≤ 5.0 mia/L
• Consent not obtainable
• Do not resuscitate order

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Shock induced endotheliopaty	Up to 30 days	Mortality

Trial Locations

Locations (1)

Bispebjerg Hospital; 🇩🇰 Copenhagen, Copenhagen NV, Denmark