Comparison of the effect of Bisphosphonate on the prevention of type 2 diabetes among Osteopenic menopause prediabetes women and Referred to Isfahan Endocrine and Metabolism Research Center.
Phase 2
- Conditions
- Prediabetes.Impaired glucose tolerance, Menopausal and other perimenopausal disorders, Postmenopausal osteoporosisR73, N95,
- Registration Number
- IRCT2016101530309N1
- Lead Sponsor
- Vice chancellor for research, Isfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 60
Inclusion Criteria
Inclusion and exclusion criteria
Inclusion criteria
Prediabetes and menopause female patients who are resistant to insulin at age between 45 to 60 will be included if fulfilling the following two criteria:
Osteopenia based on bone density measured by DAX machine Hologic 2008 model; Written consent by the patient to participate in the study obtained at the baseline
Exclusion criteria
Patients fulfilling any of the following criteria will be excluded from the study; Failure to use vitamin of OTC or trace element; Patients who do not like to continue with the study for any reason; Patients who take drugs that affect metabolism of glucose; The Osteoporotic patient; Patients with kidney failure problem.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 25 OH D3. Timepoint: Before and three months after the study. Method of measurement: Blood test.;Plasma glucose, Insulin Sensitivity and Insulin Resistance, HbA1C. Timepoint: Before and three months after the study. Method of measurement: Blood test.;Lipid Profile TG - Total Cholostrol LDL-HDL. Timepoint: Before and three months after the study. Method of measurement: Blood test.
- Secondary Outcome Measures
Name Time Method