The hemostatic effect of local injection of tranexamic acid into peri-articular tissue in total knee arthroplasty
Not Applicable
- Conditions
- Osteoarthritis of the knee Rheumatoid arthritis
- Registration Number
- JPRN-UMIN000036146
- Lead Sponsor
- Department of Orthopedic Surgery, Hakodate Orthopedic Clinic, Japan
- Brief Summary
The calculated total blood loss (CTBL) in groups L and D was nearly equal and did not show the non-inferiority of group L to group D (883 vs. 841 ml, P .564). Drained blood loss was significantly higher in group L than in group D (395 vs 276 ml, P .0001). There was no significant difference in hidden blood loss between the groups (488 vs 565 ml, P .131). The other laboratory findings and physical measurements were identical between the groups.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Not provided
Exclusion Criteria
Patient with a history of thrombosis Patient with a severe renal disfunction Patients who need to restart internal anticoagulant as soon as possible postoperatively Patients deemed inappropriate as research subjects
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method