The Effects of Resveratrol on Endometriosis

Phase 2

• Conditions: Endometriosis.; Endometriosis

• Registration Number: IRCT2015101724569N1
• Lead Sponsor: Vice chancellor for research,Tehran University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

No usage of hormonal drugs; hormonal contraceptives; IUDs and supplements during the last three months before the first biopsy; no contraindication of resveratrol such as allergy to grape and green tea; no current suffering from autoimmune or known intestinal diseases; no history of pregnancy or lactation during the last 3 months;Age 18-37 years old; Body mass index between 18.5 to 30 kilograms per square meter.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Experission of VEGF gene. Timepoint: Before and after intervention. Method of measurement: RT-PCR.;Experission of MMP9 gene. Timepoint: Before and after intervention. Method of measurement: RT-PCR.;Experission of MMP2 gene. Timepoint: Before and after intervention. Method of measurement: RT-PCR.;Experission of the PRb gene and protein. Timepoint: Before and after intervention. Method of measurement: Western Blot and RT-PCR.;Experission of the PRA gene and protein. Timepoint: Before and after intervention. Method of measurement: Western Blot and RT-PCR.;Experission of IL1b gene and protein. Timepoint: Before and after intervention. Method of measurement: Western Blot and RT-PCR.;Experission of IL8 gene. Timepoint: Before and after intervention. Method of measurement: RT-PCR.;Experission the gene and TNF alpha protein. Timepoint: Before and after intervention. Method of measurement: Western Blot and RT-PCR.