The effect of resveratrol on diabetes treatment

Phase 3

Conditions: Type 2 diabetes.
Non-insulin-dependent diabetes mellitus

Registration Number: IRCT2015072523336N1

Lead Sponsor: Vice chancellor of Research, Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 60

Inclusion Criteria

Ability to give informed consent; Age 40-60 years; Diabetic patients with BMI less than 35 kg/m2; Lack of insulin therapy; HbA1c > 7.5.
Exclusion criteria: Subjects on any antioxidant medication; Patient on non-steroidal anti-inflammatory drug; Patients on insulin therapy; Patients with severe diabetic complications such as nephropathy , retinopathy and amputation; On any agent with significant antioxidant properties; History of alcohol abuse; Any life threatening disease such as cancer and infectious diseases; Allergy to peanuts, grapes, wine, mulberries; Pregnant women; Coronary event or procedure (myocardial infarction, unstable angina, coronary artery bypass surgery or coronary angioplasty) in the previous four weeks; Subjects on anticoagulants; History of recent taking red grapes, pistachios, almonds and berries; ALT and/or AST > 2 times above upper limit of normal.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
HbA1c. Timepoint: Before and two months after intervention. Method of measurement: HPLC.;FBS. Timepoint: Before and two months after intervention. Method of measurement: Enzymatic reaction.;Reactive oxygen species (ROS). Timepoint: Before and two months after intervention. Method of measurement: Flow cytometry.

Secondary Outcome Measures