Evaluation of the effects of Resveratrol on serum TNF-a and hs-CRPand quality of life in patients with ulcerative colitis.

Phase 2

• Conditions: ulcerative colitis.; Ulcerative colitis, unspecified

• Registration Number: IRCT201209154010N10
• Lead Sponsor: ational Nutrition and Food Technology Research Institute (NNFTRI)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Age of 18 years and older; BMI between 18.5-30; histopathologic findings compatible with ulcerative colitis (mild-moderate active). Exclusion criteria: other enteral, autoimmune, inflammatory diseases and cancers; Pregnancy & Breast feeding, use of oral contraceptive drugs, using multivitamins, minerals, omega-3, poly phenolic and anti oxidant supplements in previous month, Use of drugs such as calcium channel blockers, NSAIDs, heparin ,varfarin and anti histamin in previous month; changes in dosage and kind of drugs in previous month and changes in dosage and kind of drugs during intervention; activation of disease resulting to hospitalization; reluctancy to continue.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of life (IBDQ-9). Timepoint: at weeks: 0 and 6. Method of measurement: questionnarie.;Serum TNF-a. Timepoint: at weeks: 0 and 6. Method of measurement: ELISA.;Serum hs-CRP. Timepoint: at weeks: 0 and 6. Method of measurement: ELISA.

Secondary Outcome Measures

Name	Time	Method
Weight and BMI. Timepoint: at weeks: 0 and 6. Method of measurement: Weight will be measured by Secca scale , BMI by formula.;Waist circumference, hip circumfereance. Timepoint: at weeks: 0 and 6. Method of measurement: non stretch meter.;Height. Timepoint: at weeks: 0 and 6. Method of measurement: non stretch meter.