NCT05145504CompletedNot Applicable
Evaluation of Biomarker IL-6 in Synovial Fluid in Obese and Normal Weight Patients Suffering From Gonarthrosis During Knee Arthroplasty Surgery.
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio1 site in 1 country37 target enrollmentStarted: November 18, 2021Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 37
- Locations
- 1
- Primary Endpoint
- Evaluate whether the IL-6 concentration in the synovial fluid of obese patients is 100% higher than the IL-6 concentration of the synovial fluid in normal weight patients
Study Overview
Brief Summary
Evaluate the concentration of IL-6 in the synovial fluid of obese patients suffering from gonarthrosis during knee arthroplasty surgery
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 55 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •age between 55 and 85 years inclusive,
- •Normal weight patients with BMI 18-24.9 included
- •Obese patients with BMI ≥ 30
- •Patients suffering from gonarthrosis awaiting knee arthroplasty surgery
- •Patients awaiting knee replacement surgery
- •Patients who agree to sign informed consent
Exclusion Criteria
- •Patients under 55 years of age.
- •Patients over 85 years of age
- •Patients suffering from diabetes mellitus
- •Patients who are unable to understand
- •Patients with severe neurological disorders or severe disability
- •Rheumatoid arthritis patients
- •Cancer patients
- •Patients on immunosuppressive therapy
Outcomes
Primary Outcomes
Evaluate whether the IL-6 concentration in the synovial fluid of obese patients is 100% higher than the IL-6 concentration of the synovial fluid in normal weight patients
Time Frame: 1 day
Secondary Outcomes
No secondary outcomes reported
Investigators
Study Sites (1)
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